Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population
نویسندگان
چکیده
منابع مشابه
Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population.
Werner syndrome (WS) is a premature aging disease caused by a mutation in the WRN gene. The gene was identified in 1996 and its product acts as a DNA helicase and exonuclease. Some specific WRN polymorphic variants were associated with increased risk for cardiovascular diseases. The identification of genetic polymorphisms as risk factors for complex diseases affecting older people can improve t...
متن کاملTrauma-Related Morbidity and Mortality in Elderly Patients
Objectives: The purpose of this multi-center study was to investigate the probable predictive factors of mortality and morbidity in elderlypopulation. Methods & Materials: The descriptive prospective study was conducted based on the data gathered from trauma cases older than 65 years admitted to Sina, Shohada and Fayaz-Bakhsh trauma centers during years 1997-98. A pre-prepared questionnaire ...
متن کاملApolipoprotein E polymorphism distribution in an elderly Brazilian population: the Bambuí Health and Aging Study.
Apolipoprotein E (ApoE) is one of the most extensively studied genes in the context of aging, but there are few population-based studies on ApoE polymorphism in the elderly in developing countries. The objective of the present study was to assess ApoE allele and genotype distribution in a large elderly community-based sample and its association with age, sex and skin color. Participants include...
متن کاملdevelopment and implementation of an optimized control strategy for induction machine in an electric vehicle
in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...
15 صفحه اولFREQUENCY OF C3435 MDR1 AND A6896G CYP3A5 SINGLE NUCLEOTIDE POLYMORPHISM IN AN IRANIAN POPULATION AND COMPARISON WITH OTHER ETHNIC GROUPS
ABSTRACT Background: It is well recognized that different patients respond in different ways to medications. The inter-individual variations are greater than the intera- individual variations, a finding consistent with the notion that inheritance is a determinant of drug responses. The recent identification of genetic polymorphisms in drug-metabolizing enzymes and drug transporters led to the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 2005
ISSN: 0100-879X
DOI: 10.1590/s0100-879x2005000700008